1. Get drug

Returns drug data with project related connections.

1.1. CURL sample 1

$ curl 'https://minerva-service.lcsb.uni.lu/minerva/api/projects/test_project/drugs:search?query=aspirin' -X GET \
    --cookie "MINERVA_AUTH_TOKEN=xxxxxxxx"

1.2. CURL sample 2

$ curl 'https://minerva-service.lcsb.uni.lu/minerva/api/projects/Some_id/drugs:search?target=ALIAS:488' -X GET \
    --cookie "MINERVA_AUTH_TOKEN=xxxxxxxx"

1.3. Path Parameters

Table 1. /minerva/api/projects/{projectId}/drugs:search
Parameter Description

projectId

project identifier

1.4. Request Parameters

Parameter Description

columns

set of columns (all by default). Available options: name, references, description, synonyms, id, directEvidenceReferences, directEvidence, targets

query

name of chemical that we are searching for

target

target element that we are searching for in format TYPE:ID

1.5. Response Fields

Path Type Description

[].id

String

identifier of the chemical

[].name

String

name

[].description

String

description

[].synonyms

array<string>

list of synonyms

[].brandNames

array<string>

list of brand names

[].bloodBrainBarrier

String

does drug cross blood brain barrier

[].references

array<Reference>

list of references

[].targets

array<Target>

list of targets

[].targets[].name

String

target name

[].targets[].references

array<Reference>

list of target references

[].targets[].source

Object

source database of the target

[].targets[].targetElements

array<object>

list of elements on the map associated with this target

[].targets[].targetParticipants

array<object>

list of identifiers associated with this target

1.6. Sample Response

[ {
  "name" : "Acetylsalicylic acid",
  "references" : [ {
    "link" : "https://go.drugbank.com/drugs/DB00945",
    "type" : "DRUGBANK",
    "resource" : "DB00945",
    "id" : 0,
    "annotatorClassName" : ""
  }, {
    "link" : "https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL25",
    "type" : "CHEMBL_COMPOUND",
    "resource" : "CHEMBL25",
    "id" : 0,
    "annotatorClassName" : ""
  } ],
  "description" : "Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects.  This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label].  \n\nInterestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. \n\nAcetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].",
  "bloodBrainBarrier" : "N/A",
  "brandNames" : [ "Adiro", "Solprin", "Easprin", "Acetophen\n      Merck", "Aspergum", "Solprin acid", "St. Joseph Aspirin for Adults", "Aspro", "Nu-seals", "Rhodine", "Tasprin", "Rhonal", "Acenterine", "Empirin" ],
  "synonyms" : [ "O-acetylsalicylic acid", "Aspirina", "Aspirin", "o-carboxyphenyl acetate", "Acide acétylsalicylique", "2-Acetoxybenzenecarboxylic acid", "Azetylsalizylsäure", "ASA", "Acetylsalicylsäure", "Acetylsalicylate", "2-Acetoxybenzoic acid", "acide 2-(acétyloxy)benzoïque", "ácido acetilsalicílico", "Polopiryna", "Acidum acetylsalicylicum", "salicylic acid acetate", "o-acetoxybenzoic acid", "8-HOUR BAYER", "Acetosalic Acid", "ACETYLSALIC ACID", "ACETYL SALICYLATE", "ACETYLSALICYLIC ACID", "ACETYLSALICYLIC ACID (WHO-IP)", "ACETYLSALICYLICUM ACIDUM", "ACIDUM ACETYLSALICYLICUM", "ACIDUM ACETYLSALICYLICUM (WHO-IP)", "ALKA RAPID", "ANADIN ALL NIGHT", "ANGETTES 75", "ASPIRIN", "ASPIRIN COMPONENT OF AGGRENOX", "ASPIRIN COMPONENT OF AXOTAL", "ASPIRIN COMPONENT OF AZDONE", "ASPIRIN COMPONENT OF CARISOPRODOL COMPOUND", "ASPIRIN COMPONENT OF CLOPIDOGREL/ACETYLSALICYLIC ACID", "ASPIRIN COMPONENT OF CODOXY", "ASPIRIN COMPONENT OF DARVON COMPOUND", "ASPIRIN COMPONENT OF DUOCOVER", "ASPIRIN COMPONENT OF DUOPLAVIN", "ASPIRIN COMPONENT OF EQUAGESIC", "ASPIRIN COMPONENT OF EXCEDRIN", "ASPIRIN COMPONENT OF FIORINAL", "ASPIRIN COMPONENT OF INVAGESIC", "ASPIRIN COMPONENT OF INVAGESIC FORTE", "ASPIRIN COMPONENT OF LANORINAL", "ASPIRIN COMPONENT OF MEPRO-", "ASPIRIN COMPONENT OF MICRAININ", "ASPIRIN COMPONENT OF NORGESIC", "ASPIRIN COMPONENT OF ORPHENGESIC", "ASPIRIN COMPONENT OF ORPHENGESIC FORTE", "ASPIRIN COMPONENT OF PA-32540", "ASPIRIN COMPONENT OF -PC", "ASPIRIN COMPONENT OF PERCODAN", "ASPIRIN COMPONENT OF PERCODAN-DEMI", "ASPIRIN COMPONENT OF PL2200", "ASPIRIN COMPONENT OF PRAVIGARD PAC", "ASPIRIN COMPONENT OF Q-GESIC", "ASPIRIN COMPONENT OF ROBAXISAL", "ASPIRIN COMPONENT OF ROXIPRIN", "ASPIRIN COMPONENT OF SOMA COMPOUND", "ASPIRIN COMPONENT OF SYNALGOS-DC", "ASPIRIN COMPONENT OF TALWIN COMPOUND", "ASPIRIN COMPONENT OF VICOPRIN", "ASPIRIN COMPONENT OF YOSPRALA", "ASPRO CLR", "BAY1019036", "BAYER EXTRA STRENGTH ASPIRIN FOR MIGRAINE PAIN", "BENZOIC ACID, 2-(ACETYLOXY)-", "DANAMEP", "DISPRIN CV", "DISPRIN DIRECT", "DURLAZA", "ENPRIN", "Equi-Prin", "GENCARDIA", "LEVIUS", "MAX STRGH ASPRO CLR", "MEASURIN", "MICROPIRIN EC", "NSC-27223", "NSC-406186", "NU-SEALS 300", "NU-SEALS 600", "NU-SEALS 75", "NU-SEALS CARDIO 75", "PAYNOCIL", "PLATET", "PLATET 300", "POSTMI 300", "POSTMI 75", "Salicylic Acid Acetate", "VAZALORE" ],
  "id" : "Acetylsalicylic acid",
  "targets" : [ {
    "source" : {
      "link" : null,
      "type" : "DRUGBANK_TARGET_V4",
      "resource" : "BE0004907",
      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "5'-AMP-activated protein kinase",
    "targetParticipants" : [ {
      "link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/PRKAA1",
      "type" : "HGNC_SYMBOL",
      "resource" : "PRKAA1",
      "id" : 0,
      "annotatorClassName" : ""
    } ],
    "references" : [ {
      "link" : "https://pubmed.ncbi.nlm.nih.gov/22517326/",
      "article" : null,
      "type" : "PUBMED",
      "resource" : "22517326",
      "id" : 0,
      "annotatorClassName" : ""
    }, {
      "link" : "https://pubmed.ncbi.nlm.nih.gov/23871515/",
      "article" : null,
      "type" : "PUBMED",
      "resource" : "23871515",
      "id" : 0,
      "annotatorClassName" : ""
    }, {
      "link" : "https://pubmed.ncbi.nlm.nih.gov/22406476/",
      "article" : null,
      "type" : "PUBMED",
      "resource" : "22406476",
      "id" : 0,
      "annotatorClassName" : ""
    } ],
    "targetElements" : [ ]
  }, {
    "source" : {
      "link" : null,
      "type" : "DRUGBANK_TARGET_V4",
      "resource" : "BE0001098",
      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "78 kDa glucose-regulated protein",
    "targetParticipants" : [ {
      "link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/HSPA5",
      "type" : "HGNC_SYMBOL",
      "resource" : "HSPA5",
      "id" : 0,
      "annotatorClassName" : ""
    } ],
    "references" : [ {
      "link" : "https://pubmed.ncbi.nlm.nih.gov/11689471/",
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      "type" : "PUBMED",
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    "targetElements" : [ ]
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      "link" : null,
      "type" : "DRUGBANK_TARGET_V4",
      "resource" : "BE0000126",
      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "Aldo-keto reductase family 1 member C1",
    "targetParticipants" : [ {
      "link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/AKR1C1",
      "type" : "HGNC_SYMBOL",
      "resource" : "AKR1C1",
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    "references" : [ {
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      "type" : "DRUGBANK_TARGET_V4",
      "resource" : "BE0000444",
      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "Caspase-1",
    "targetParticipants" : [ {
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    "name" : "Inhibitor of nuclear factor kappa-B kinase subunit beta",
    "targetParticipants" : [ {
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    "targetElements" : [ ]
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      "type" : "DRUGBANK_TARGET_V4",
      "resource" : "BE0004689",
      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "Myc proto-oncogene protein",
    "targetParticipants" : [ {
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      "type" : "HGNC_SYMBOL",
      "resource" : "MYC",
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      "annotatorClassName" : ""
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    "references" : [ {
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    "targetElements" : [ ]
  }, {
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      "type" : "DRUGBANK_TARGET_V4",
      "resource" : "BE0003469",
      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "NF-kappa-B inhibitor alpha",
    "targetParticipants" : [ {
      "link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/NFKBIA",
      "type" : "HGNC_SYMBOL",
      "resource" : "NFKBIA",
      "id" : 0,
      "annotatorClassName" : ""
    } ],
    "references" : [ {
      "link" : "https://pubmed.ncbi.nlm.nih.gov/10553090/",
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      "type" : "PUBMED",
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    } ],
    "targetElements" : [ ]
  }, {
    "source" : {
      "link" : null,
      "type" : "DRUGBANK_TARGET_V4",
      "resource" : "BE0009667",
      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "Nuclear factor kappa b beta subunit",
    "targetParticipants" : [ ],
    "references" : [ {
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    "targetElements" : [ ]
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      "type" : "DRUGBANK_TARGET_V4",
      "resource" : "BE0009045",
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    },
    "name" : "Proliferating cell nuclear antigen",
    "targetParticipants" : [ {
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      "type" : "HGNC_SYMBOL",
      "resource" : "PCNA",
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      "annotatorClassName" : ""
    } ],
    "references" : [ {
      "link" : "https://pubmed.ncbi.nlm.nih.gov/15068834/",
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    "targetElements" : [ ]
  }, {
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    "targetParticipants" : [ {
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    "targetElements" : [ ]
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      "annotatorClassName" : ""
    },
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    "targetElements" : [ ]
  }, {
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      "type" : "DRUGBANK_TARGET_V4",
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      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "Ribosomal protein S6 kinase alpha-3",
    "targetParticipants" : [ {
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      "type" : "HGNC_SYMBOL",
      "resource" : "RPS6KA3",
      "id" : 0,
      "annotatorClassName" : ""
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      "link" : "https://pubmed.ncbi.nlm.nih.gov/21142801/",
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    } ],
    "targetElements" : [ ]
  }, {
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      "type" : "DRUGBANK_TARGET_V4",
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      "id" : 0,
      "annotatorClassName" : ""
    },
    "name" : "Tumor necrosis factor-inducible gene 6 protein",
    "targetParticipants" : [ {
      "link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/TNFAIP6",
      "type" : "HGNC_SYMBOL",
      "resource" : "TNFAIP6",
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} ]

2. Get suggested drug queries

Get list of suggested drug queries in the context of the project.

2.1. CURL sample

$ curl 'https://minerva-service.lcsb.uni.lu/minerva/api/projects/test_project/drugs/suggestedQueryList' -X GET \
    --cookie "MINERVA_AUTH_TOKEN=xxxxxxxx"

2.2. Path Parameters

Table 2. /minerva/api/projects/{projectId}/drugs/suggestedQueryList
Parameter Description

projectId

project identifier

2.3. Response Fields

Path Type Description

[]

array<string>

list of suggested drug queries

2.4. Sample Response

[ ]