1. Get drug
Returns drug data with project related connections.
1.1. CURL sample 1
$ curl 'https://minerva-service.lcsb.uni.lu/minerva/api/projects/test_project/drugs:search?query=aspirin' -X GET \
--cookie "MINERVA_AUTH_TOKEN=xxxxxxxx"
1.2. CURL sample 2
$ curl 'https://minerva-service.lcsb.uni.lu/minerva/api/projects/Some_id/drugs:search?target=ALIAS:75' -X GET \
--cookie "MINERVA_AUTH_TOKEN=xxxxxxxx"
1.3. Path Parameters
| Parameter | Description |
|---|---|
|
project identifier |
1.4. Request Parameters
| Parameter | Description |
|---|---|
|
set of columns (all by default). Available options: name, references, description, synonyms, id, directEvidenceReferences, directEvidence, targets |
|
name of chemical that we are searching for |
|
target element that we are searching for in format TYPE:ID |
1.5. Response Fields
| Path | Type | Description |
|---|---|---|
|
|
identifier of the chemical |
|
|
name |
|
|
description |
|
|
list of synonyms |
|
|
list of brand names |
|
|
does drug cross blood brain barrier |
|
|
list of references |
|
|
list of targets |
|
|
target name |
|
|
list of target references |
|
|
source database of the target |
|
|
list of elements on the map associated with this target |
|
|
list of identifiers associated with this target |
1.6. Sample Response
[ {
"name" : "Acetylsalicylic acid",
"references" : [ {
"link" : "https://go.drugbank.com/drugs/DB00945",
"type" : "DRUGBANK",
"resource" : "DB00945",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL25",
"type" : "CHEMBL_COMPOUND",
"resource" : "CHEMBL25",
"id" : 0,
"annotatorClassName" : ""
} ],
"description" : "Also known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. \n\nInterestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. \n\nAcetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].",
"bloodBrainBarrier" : "N/A",
"brandNames" : [ "Adiro", "Solprin", "Easprin", "Acetophen\n Merck", "Aspergum", "Solprin acid", "St. Joseph Aspirin for Adults", "Aspro", "Nu-seals", "Rhodine", "Tasprin", "Rhonal", "Acenterine", "Empirin", "8-hour bayer", "Acetosalic Acid", "Acetylsalic acid", "Acetylsalicylic Acid", "Alka rapid", "Anadin all night", "Angettes 75", "Aspirin", "Aspro clr", "Bayer extra strength aspirin for migraine pain", "Danamep", "Disprin cv", "Disprin direct", "Durlaza", "Ecotrin", "Enprin", "Equi-Prin", "Gencardia", "Levius", "Max strgh aspro clr", "Measurin", "Micropirin ec", "Nu-seals 300", "Nu-seals 600", "Nu-seals 75", "Nu-seals cardio 75", "Paynocil", "Platet", "Platet 300", "Postmi 300", "Postmi 75", "Salicylic Acid Acetate", "Vazalore" ],
"synonyms" : [ "O-acetylsalicylic acid", "Aspirina", "Aspirin", "o-carboxyphenyl acetate", "Acide ac��tylsalicylique", "2-Acetoxybenzenecarboxylic acid", "Azetylsalizyls��ure", "ASA", "Acetylsalicyls��ure", "Acetylsalicylate", "2-Acetoxybenzoic acid", "acide 2-(ac��tyloxy)benzo��que", "��cido acetilsalic��lico", "Polopiryna", "Acidum acetylsalicylicum", "salicylic acid acetate", "o-acetoxybenzoic acid", "Acetyl salicylate", "Acetylsalicylic Acid", "Acetylsalicylic acid", "Acetylsalicylic acid (who-ip)", "Acetylsalicylicum acidum", "Acidum acetylsalicylicum (who-ip)", "BAY1019036", "Benzoic acid, 2-(acetyloxy)-", "NSC-27223", "NSC-406186" ],
"id" : "Acetylsalicylic acid",
"targets" : [ {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0004907",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "5'-AMP-activated protein kinase",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/PRKAA1",
"type" : "HGNC_SYMBOL",
"resource" : "PRKAA1",
"id" : 0,
"annotatorClassName" : ""
} ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/22517326/",
"article" : null,
"type" : "PUBMED",
"resource" : "22517326",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/23871515/",
"article" : null,
"type" : "PUBMED",
"resource" : "23871515",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/22406476/",
"article" : null,
"type" : "PUBMED",
"resource" : "22406476",
"id" : 0,
"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0001098",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "78 kDa glucose-regulated protein",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/HSPA5",
"type" : "HGNC_SYMBOL",
"resource" : "HSPA5",
"id" : 0,
"annotatorClassName" : ""
} ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/11689471/",
"article" : null,
"type" : "PUBMED",
"resource" : "11689471",
"id" : 0,
"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0000126",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Aldo-keto reductase family 1 member C1",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/AKR1C1",
"type" : "HGNC_SYMBOL",
"resource" : "AKR1C1",
"id" : 0,
"annotatorClassName" : ""
} ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/18045204/",
"article" : null,
"type" : "PUBMED",
"resource" : "18045204",
"id" : 0,
"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0000444",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Caspase-1",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/CASP1",
"type" : "HGNC_SYMBOL",
"resource" : "CASP1",
"id" : 0,
"annotatorClassName" : ""
} ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/23110215/",
"article" : null,
"type" : "PUBMED",
"resource" : "23110215",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/24874482/",
"article" : null,
"type" : "PUBMED",
"resource" : "24874482",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/26980842/",
"article" : null,
"type" : "PUBMED",
"resource" : "26980842",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/30693272/",
"article" : null,
"type" : "PUBMED",
"resource" : "30693272",
"id" : 0,
"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0001162",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Caspase-3",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/CASP3",
"type" : "HGNC_SYMBOL",
"resource" : "CASP3",
"id" : 0,
"annotatorClassName" : ""
} ],
"references" : [ {
"link" : null,
"article" : null,
"type" : "PUBMED",
"resource" : "23110215",
"id" : 0,
"annotatorClassName" : ""
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"link" : null,
"article" : null,
"type" : "PUBMED",
"resource" : "24874482",
"id" : 0,
"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0003380",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Cellular tumor antigen p53",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/TP53",
"type" : "HGNC_SYMBOL",
"resource" : "TP53",
"id" : 0,
"annotatorClassName" : ""
} ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/21475861/",
"article" : null,
"type" : "PUBMED",
"resource" : "21475861",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/26596838/",
"article" : null,
"type" : "PUBMED",
"resource" : "26596838",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/24726874/",
"article" : null,
"type" : "PUBMED",
"resource" : "24726874",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/12535653/",
"article" : null,
"type" : "PUBMED",
"resource" : "12535653",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/17510082/",
"article" : null,
"type" : "PUBMED",
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} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0009669",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Cyclin A",
"targetParticipants" : [ ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/26685215/",
"article" : null,
"type" : "PUBMED",
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"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0000521",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Endothelin-1 receptor",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/EDNRA",
"type" : "HGNC_SYMBOL",
"resource" : "EDNRA",
"id" : 0,
"annotatorClassName" : ""
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"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/10727528/",
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"type" : "PUBMED",
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"targetElements" : [ ]
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"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0009668",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Extracellular signal-regulated kinase (ERK)",
"targetParticipants" : [ ],
"references" : [ {
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"article" : null,
"type" : "PUBMED",
"resource" : "24874482",
"id" : 0,
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"id" : 0,
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"link" : "https://pubmed.ncbi.nlm.nih.gov/24026640/",
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} ],
"targetElements" : [ ]
}, {
"source" : {
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"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0001027",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "G1/S-specific cyclin-D1",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/CCND1",
"type" : "HGNC_SYMBOL",
"resource" : "CCND1",
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"annotatorClassName" : ""
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"references" : [ {
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"type" : "PUBMED",
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"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0001154",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Inhibitor of nuclear factor kappa-B kinase subunit beta",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/IKBKB",
"type" : "HGNC_SYMBOL",
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"type" : "PUBMED",
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"id" : 0,
"annotatorClassName" : ""
}, {
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"article" : null,
"type" : "PUBMED",
"resource" : "24874482",
"id" : 0,
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"id" : 0,
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"type" : "PUBMED",
"resource" : "11160126",
"id" : 0,
"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0004689",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Myc proto-oncogene protein",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/MYC",
"type" : "HGNC_SYMBOL",
"resource" : "MYC",
"id" : 0,
"annotatorClassName" : ""
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"references" : [ {
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"article" : null,
"type" : "PUBMED",
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"id" : 0,
"annotatorClassName" : ""
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"type" : "PUBMED",
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"article" : null,
"type" : "PUBMED",
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"annotatorClassName" : ""
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"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0003469",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "NF-kappa-B inhibitor alpha",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/NFKBIA",
"type" : "HGNC_SYMBOL",
"resource" : "NFKBIA",
"id" : 0,
"annotatorClassName" : ""
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"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/10553090/",
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"type" : "PUBMED",
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"id" : 0,
"annotatorClassName" : ""
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"targetElements" : [ ]
}, {
"source" : {
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"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0009667",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Nuclear factor kappa b beta subunit",
"targetParticipants" : [ ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/28718829/",
"article" : null,
"type" : "PUBMED",
"resource" : "28718829",
"id" : 0,
"annotatorClassName" : ""
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"link" : "https://pubmed.ncbi.nlm.nih.gov/9817203/",
"article" : null,
"type" : "PUBMED",
"resource" : "9817203",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/29301759/",
"article" : null,
"type" : "PUBMED",
"resource" : "29301759",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/21303813/",
"article" : null,
"type" : "PUBMED",
"resource" : "21303813",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/8052854/",
"article" : null,
"type" : "PUBMED",
"resource" : "8052854",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/28278500/",
"article" : null,
"type" : "PUBMED",
"resource" : "28278500",
"id" : 0,
"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0009045",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Proliferating cell nuclear antigen",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/PCNA",
"type" : "HGNC_SYMBOL",
"resource" : "PCNA",
"id" : 0,
"annotatorClassName" : ""
} ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/15068834/",
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"type" : "PUBMED",
"resource" : "15068834",
"id" : 0,
"annotatorClassName" : ""
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"type" : "PUBMED",
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"article" : null,
"type" : "PUBMED",
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"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0000017",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Prostaglandin G/H synthase 1",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/PTGS1",
"type" : "HGNC_SYMBOL",
"resource" : "PTGS1",
"id" : 0,
"annotatorClassName" : ""
} ],
"references" : [ {
"link" : "https://pubmed.ncbi.nlm.nih.gov/17259075/",
"article" : null,
"type" : "PUBMED",
"resource" : "17259075",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/17319904/",
"article" : null,
"type" : "PUBMED",
"resource" : "17319904",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/17131625/",
"article" : null,
"type" : "PUBMED",
"resource" : "17131625",
"id" : 0,
"annotatorClassName" : ""
}, {
"link" : "https://pubmed.ncbi.nlm.nih.gov/17078596/",
"article" : null,
"type" : "PUBMED",
"resource" : "17078596",
"id" : 0,
"annotatorClassName" : ""
} ],
"targetElements" : [ ]
}, {
"source" : {
"link" : null,
"type" : "DRUGBANK_TARGET_V4",
"resource" : "BE0000262",
"id" : 0,
"annotatorClassName" : ""
},
"name" : "Prostaglandin G/H synthase 2",
"targetParticipants" : [ {
"link" : "https://www.genenames.org/data/gene-symbol-report/#!/symbol/PTGS2",
"type" : "HGNC_SYMBOL",
"resource" : "PTGS2",
"id" : 0,
"annotatorClassName" : ""
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2. Get suggested drug queries
Get list of suggested drug queries in the context of the project.
2.1. CURL sample
$ curl 'https://minerva-service.lcsb.uni.lu/minerva/api/projects/test_project/drugs/suggestedQueryList' -X GET \
--cookie "MINERVA_AUTH_TOKEN=xxxxxxxx"
2.2. Path Parameters
| Parameter | Description |
|---|---|
|
project identifier |
2.3. Response Fields
| Path | Type | Description |
|---|---|---|
|
|
list of suggested drug queries |
2.4. Sample Response
[ ]